Deinococcus radiodurans

273 mots 2 pages
Deinococcus radiodurans

History
D. radiodurans was discovered in 1956 by Arthur W. Anderson at the Oregon Agricultural Experiment Station in Corvallis. Experiments were being performed to determine if canned food like tin of meat could be sterilized using high doses of gamma radiation but the decomposition process doesn’t stop, and the bacteria was isolated.
This bacteria was a deinococcus radiodurans and nicknamed “Conan the bacterium” referred to “Conan the barbarian” because of his hardiness.
Gram-positive, red-pigmented. Four cells normally stick together ( Chomosom I 2,648,638 bp and II 412,348 bp , a plasmid CP 45,704 bp and a megaplasmid MP1 177,466 bp >100kpb).
Maybe origin from mars. Characteristics
It is often found in habitats rich in organic materials, such as soil, meat, or sewage, but has also been isolated from dried foods, or medical instruments.
It’s one of the most radioresistant organisms known.
It’s a polyextremophile bacteria because it resists to ionizing radiation, ultraviolet light, desiccation, hydrogen peroxide, vacuum, acid, and extremes of temperature.
DNA process
D.Radiodurans can survive because of a DNA repair process. It isolates the damaged segments in a controlled area and repairs it. This bacteria can also repair many small fragments from an entire chromosome.
It usually repairs breaks in its chromosomes within 12–24 hours through a 2-step process .
First, D. radiodurans reconnects some chromosome fragments through a process called single-strand annealing. In the second step, a protein mends double-strand breaks through homologous recombination.
One of the main application is the bioremediation to consume and digest solvents and heavy metals, even in a highly radioactive

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